With the improvement of people's living standard and the change of social population structure, the influence of cardiovascular disease risk factors such as hypertension and hyperlipidemia on residents' health Bigger and bigger. According to the 2020 edition of the China Cardiovascular Health and Disease Report, cardiovascular disease is the leading cause of death among urban and rural residents The number of people with related diseases now stands at 330 million. Patients with cardiovascular disease tend to be older and need long-term medication, but different people are taking the same medication There may be significant differences in clinical outcomes for amounts of the same drug, including poor efficacy, ineffectiveness, or increased risk of side effects.

In 2015, the Medical Administration Administration of the National Health and Family Planning Commission issued the Technical Guidelines for the Detection of Drug Metabolizing Enzymes and Drug Target Genes (Trial), suggesting Clinicians treated ADRB1(G1165C), SLCO1B1(521T> C), ALDH2*2, CYP2C19*2*3*17 and other genes To improve the effectiveness and safety of medication.