Customs entry and exit infectious disease monitoring - RocGene (Beijing) Technology Co., Ltd.

Application Requirements

There may be incubation infected people or asymptomatic carriers among entry and exit personnel, and their pathogen loads are low, and traditional methods are easy to miss detection. The timeliness of the gate test is high, and the test results need to be submitted in a short time. During the experiment, the sample may contain interfering substances (such as hemoglobin in the blood, mucin in saliva), which is prone to false negative or false positive results. Therefore, molecular detection systems with stronger sample processing capabilities, higher specificity and sensitivity are needed to provide fast and accurate detection services.

Solutions

Point-of-Care Testing (POCT) Solution - iFIND

Sample Processing: Built-in ultrasound combined with chemical lysis + high-efficiency microfiltration membrane purification.
System Construction: Fully enclosed cartridge, prefabricated lyophilized reagents, fully automatic system preparation.
Detection Results: Thin-film reaction zone with average temperature change rate ≥10℃/s. Ultra-multiplex detection realized by multiple probes and probe melting curve analysis.

Open Workstation Solution - Atlas120

Sample Processing: Supports fully automatic nucleic acid extraction for up to 12 samples simultaneously.
System Construction: Open detection reagents, robotic arm for automated reaction system preparation, full-process liquid sealing to avoid contamination.
Detection Results: Standard real-time fluorescent quantitative PCR reaction supporting amplification and melting curve analysis. 6-color fluorescence with 4 amplification detection positions per sample, enabling detection of up to 24 targets.

Rapid Response Solution - ArchiPure+Archimed Mini/Mini Pro

Sample Processing: Automatic nucleic acid extractor for high-purity nucleic acid extraction from samples (e.g., nasopharyngeal swabs, throat swabs), improving the sensitivity and reliability of subsequent detection.
System Construction: Manual preparation of detection system or use of Rocgene lyophilized ready-to-use reagents.
Detection Results: Real-time fluorescent quantitative PCR instrument combined with multiplex PCR technology, supporting amplification and melting curve analysis. Standard 4-color fluorescence, 16/96 throughput. Enables rapid detection of samples with various throughputs.

Standard Detection Solution - ArchiPure+Archimed X Series

Sample Processing: 16/32/96 Pro throughput automatic nucleic acid extractor for high-purity nucleic acid extraction from samples (e.g., nasopharyngeal swabs, throat swabs), improving the sensitivity and reliability of subsequent detection.
System Construction: Manual preparation of detection system or use of Rocgene lyophilized ready-to-use reagents.
Detection Results: 96-well Archimed X Series real-time fluorescent quantitative PCR instrument combined with multiplex PCR technology, supporting amplification and melting curve analysis, meeting daily detection needs for standard throughput experiments.

Application Scenarios

Department of Health Quarantine, General Administration of Customs

Formulates entry-exit health quarantine policies, technical specifications and emergency plans, and coordinates infectious disease surveillance at ports nationwide.

Customs Health Quarantine Departments

Directly undertakes on-site port detection, sample preliminary screening and emergency response.

International Travel Healthcare Centers

Provides physical examinations, infectious disease testing and health consultation for entry-exit personnel. Some institutions undertake port sample re-testing.

Customs Technical Centers

Conducts technical R&D, standard formulation and complex sample testing, providing technical support for grassroots customs.

On-site Port Testing Points and Mobile Detection Units

Performs rapid preliminary screening at airports, land ports and other sites to shorten detection time.

Detection Process

Point-of-Care Testing (POCT) Solution - iFIND

Open Workstation Solution - Atlas120

Rapid Response Solution - ArchiPure+Archimed Mini/MiniPro

Standard Detection Solution - ArchiPure+Archimed X Series

Our Advantages

High-Efficiency Detection

All solutions support multiplex detection. The POCT solution can complete virus detection within 30 minutes. The workstation and standard detection solutions save more than 20% of time compared with conventional instruments.

Excellent Sensitivity and Specificity

Combined with automatic nucleic acid extraction and high-efficiency real-time fluorescent quantitative PCR, ensuring high sensitivity and strong specificity, reducing the risk of false positive/false negative results.

Wide Applicability

Multiple solutions support various sample types (e.g., nasopharyngeal swabs, throat swabs, sputum, etc.) to meet different needs.

Flexible Solution Design

The types of detected pathogens can be customized according to market demands, with strong adaptability.

Successful Cases

Needs: A provincial customs International Travel Healthcare Center is responsible for infectious disease surveillance, international travel medical examinations and vaccinations, health consultation and healthcare services for entry-exit personnel. Its daily work requires rapid diagnosis solutions for high-risk infectious diseases.

Solution:

Through an exhibition, the center learned about our independently developed molecular POCT platform iFIND. After early technical communication and strict performance testing, combined with a multiplex detection kit, it uses sputum to conduct rapid tuberculosis testing for entry-exit personnel.

Result Display:

With the POCT solution, tuberculosis testing for outbound travelers was completed within 2 hours.

On-site Application Photo

Test Result