RocGene (Beijing) Technology Co., Ltd.
Application Requirements
In clinical diagnosis, many patients have similar symptoms (e.g., fever, cough, dyspnea) but can be caused by multiple pathogens (e.g., viruses, bacteria, or fungi). Traditional testing methods require individual testing, which is time-consuming and costly, making it difficult to provide comprehensive diagnostic information in a timely manner. Therefore, healthcare institutions and public health departments urgently need a fast, accurate, and versatile multi-pathogen testing protocol.
Solutions
Point-of-Care Testing (POCT) Solution - iFIND
Sample Processing: Built-in ultrasound combined with chemical lysis + high-efficiency microfiltration membrane purification.
Assay Preparation: Fully enclosed cartridge with pre-filled lyophilized reagents for fully automated assay preparation.
Detection Platform: Thin-film reaction zone with average temperature change rate ≥10℃/S; ultra-multiplex detection achieved by multiple probes + probe melting curve analysis.
Open Workstation Solution - Atlas120
Sample Processing: Supports fully automated nucleic acid extraction for up to 12 samples simultaneously.
Assay Preparation: Open detection reagents with robotic arm for automated reaction preparation, full liquid sealing to avoid contamination.
Detection Platform: Standard real-time fluorescent quantitative PCR reactions supporting amplification and melting curve analysis; 6-color fluorescence with 4 amplification detection positions per sample, enabling detection of 24 targets.
Rapid Detection Solution - ArchiPure 16 + Archimed Mini 16/Mini Pro
Sample Processing: High-purity nucleic acid is extracted from samples (e.g., nasopharyngeal swabs, oropharyngeal swabs) using 16-throughput fully automated nucleic acid extractor, improving the sensitivity and reliability of subsequent detection.
Assay Preparation: Manual preparation of detection system.
Detection Platform: Real-time fluorescent quantitative PCR instrument combined with multiplex PCR technology, supporting amplification and melting curve analysis; standard configuration with 4-color fluorescence and 16-throughput, enabling rapid detection of small-throughput samples.
Standard Detection Solution - ArchiPure32/96 + Archimed X
Sample Processing: High-purity nucleic acid is extracted from samples (e.g., nasopharyngeal swabs, oropharyngeal swabs) using 32/96-throughput fully automated nucleic acid extractor, improving the sensitivity and reliability of subsequent detection.
Assay Preparation: Manual preparation of detection system.
Detection Platform: Standard 96-throughput real-time fluorescent quantitative PCR instrument combined with multiplex PCR technology, supporting amplification and melting curve analysis; standard configuration with 4-color/6-color fluorescence, meeting daily detection needs of standard-throughput experiments.
Application Scenarios
  • Hospital ICU & Emergency Department
    Rapid screening of common respiratory infection pathogens in patients with fever, cough and other symptoms – POCT solution is recommended.
    Night Outpatient & Emergency Departments
    Rapid detection of multiple suspected pathogens during high-incidence periods of influenza and other diseases – Open Workstation Solution or Rapid Detection Solution is recommended.
    Small Clinics & Community Hospitals
    Small number of daily infection patients with basic detection needs only – POCT Solution and Open Workstation Solution are recommended.
    Clinical Laboratory of General Hospitals
    Large number of daily infection patients with diverse testing items – Open Workstation Solution and Standard Detection Solution are recommended.
    Third-Party Testing Centers
    Comprehensive detection services for respiratory or gastrointestinal pathogens for grassroots institutions and consumers during influenza season or sudden outbreaks – Standard Detection Solution is recommended.
Detection Workflow
Point-of-Care Testing (POCT) Solution - iFIND
Open Workstation Solution - Atlas 120
Rapid Detection Solution - ArchiPure 16 + Archimed Mini 16/Mini Pro
Our Advantages
01
High-Efficiency Detection
All solutions support multiplex detection: POCT solution completes detection within 30 minutes; Open Workstation and Standard Detection solutions save more than 20% of time compared with conventional instruments.
02
Excellent Sensitivity and Specificity
Combination of automated nucleic acid extraction and high-efficiency real-time fluorescent quantitative PCR ensures high sensitivity and strong specificity, reducing the risk of false positive/false negative results.
03
Wide Applicability
Multiple solutions support various sample types (e.g., nasopharyngeal swabs, oropharyngeal swabs, sputum, etc.) to meet different needs.
04
Flexible Solution Design
Customizable pathogen detection panels according to market demands with strong adaptability.
Success Cases

Scenario: During the flu season at the end of 2023, there was a nationwide surge in influenza-like patients, leading to difficulty in hospital treatment and risk of cross-infection.


Requirements: This year featured co-infection with multiple pathogens, resulting in an enormous testing burden on hospitals due to the large number of infected patients. At-home testing became a necessary supplement, with detection accuracy and speed as key factors.


Solution:

Online ordering was adopted for at-home sample collection and instant testing services. Conventional detection solutions with fixed throughput and slow speed could not meet the needs of a large number of patients. Therefore, service providers collaborated with third-party testing institutions to adopt our Rapid Detection Solution paired with respiratory multiplex detection reagents, providing patients with testing services featuring high pathogen coverage, fast result turnaround, and high cost-effectiveness.


Results:

Upon arrival at the laboratory, samples were scanned to collect patient information, which was automatically entered into the Archimed analysis system. ArchiPure16 completed nucleic acid extraction and purification within 9 minutes. The temperature ramp rate of Archimed Mini16 was specifically adjusted to adapt to the respiratory multiplex detection reagents purchased by the laboratory, reducing the detection time from 49 minutes (original platform) to 29 minutes. Additionally, a customized test report system was developed for the laboratory, truly achieving unattended report generation.

On-site Usage Photos
Detection Results
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